DBCO-PEG12-DBCO linker homofuncational DBCO crosslinker. It can undergo sequential copper free click chemistry with azide-tagged biomolecules to form stable triazole linkages separated by the hydrophilic PEG spacer, which provides added aqueous solubility and rotational flexibility.
DBCO-PEG12-DBCO is a bifunctional molecule that consists of two azide chemistries that are attached to a polyethylene glycol (PEG) spacer. The two azide groups are connected to the PEG spacer by a di-bromo-cyclooctyne (DBCO) group, which serves as the linker between the two azide functionalities. This molecule can be used in click-chemistry reactions to couple two molecules together, such as proteins or other biomolecules.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.