Acid but-2-enecarbonyl-Val-Ala-PAB CAS:2410723-61-2 is a type of small molecule linker that is commonly used in the field of bioconjugation and drug delivery. It consists of a valine-alanine dipeptide, which can act as a targeting moiety, and a p-aminobenzyloxycarbonyl (PAB) group, which can act as a protecting group.
The but-2-enecarbonyl group, also known as the crotonyl group, is an unsaturated carboxylic acid that can act as a reactive site for conjugation with other molecules. This allows Acid but-2-enecarbonyl-Val-Ala-PAB to be used as a linker to connect a targeting molecule, such as an antibody or peptide, with a therapeutic agent, such as a drug or toxin.
Acid but-2-enecarbonyl-Val-Ala-PAB is a versatile and effective linker that can be used to create targeted drug conjugates with improved pharmacokinetics and efficacy, as well as reduced toxicity and immunogenicity. Its use has revolutionized the field of drug delivery and bioconjugation, and it continues to be an important tool in the development of targeted therapeutics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.