3-methyl-3H-diazirin-3-propanol

3-methyl-3H-diazirin-3-propanol

This product is a diazirine-based photo-crosslinker with a terminal hydroxyl group. It specifically enables UV-activated covalent labeling of biomolecules and materials.

Key Features and Benefits

• Diazirine Group: Generates highly reactive carbenes under UV light for covalent crosslinking.

• Hydroxyl Group: Provides a handle for further derivatization or conjugation.

• Compact Design: Minimizes steric hindrance during labeling.

• Versatile Reactivity: Suitable for proteins, peptides, nucleic acids, and polymers.

• High Purity: Ensures reliable and reproducible crosslinking performance.

Applications

• Photo-crosslinking: Labels biomolecules under UV irradiation for interaction studies.

• Probe Development: Serves as a building block for photo-reactive probes.

• Material Science: Introduces photocrosslinking into polymers and nanostructures.

• Drug Discovery: Captures transient interactions in chemical biology.

Storage and Handling

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Avoid unnecessary UV exposure; use anhydrous solvents to maintain stability.

This product combines a photo-reactive diazirine group with a hydroxyl handle, specifically offering a compact scaffold for photocrosslinking and derivatization.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.