Azide-Polysarcosine (N3-polysarcosine) is a polypeptide based on the endogenous amino acid sarcosine (N-methylated glycine), the azido (N3) group reacts with alkynes, BCN, DBCO by click chemistry, Creates a stable triazole bond. pSar combines PEG-like excellent water solubility, protein resistance, low cytotoxicity, and non-immunogenicity characteristics while being based on endogenous material.
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