Mal-NH-PEG-NH2.TFA(Maleimide-NH-PEG-Amine.Trifluoroacetic acid) is a versatile compound that is widely used in pharmaceutical research and development. This compound is composed of several functional groups that make it an attractive candidate for use in drug discovery and development. The compound contains a maleimide group, which is a reactive functional group that can form covalent bonds with cysteine residues in proteins. Additionally, it contains an amine group and a polyethylene glycol (PEG) chain, which can impart solubility and biocompatibility to the compound. The trifluoroacetic acid moiety is commonly used as a cleavage agent in peptide synthesis, which makes this compound an excellent candidate for drug conjugation applications.
The maleimide functional group has found extensive use in bioconjugation chemistry, where it is used to selectively target and label proteins and peptides. The amine group in Mal-NH-PEG-NH2.TFA acid can be used to introduce a variety of functional groups, such as fluorescein, biotin, or radioactive labels, to the compound. The PEG chain in Mal-NH-PEG-NH2.TFA can be used to improve the solubility and pharmacokinetic properties of the drug, making it more effective in vivo. The trifluoroacetic acid moiety can be used to cleave peptide bonds, which is useful for the synthesis of drug conjugates.
|AP15119||Mal-NH-PEG-NH2.TFA, MW 2K||2000||≥95%||Pricing|