DBCO-PEG-SC

DBCO-PEG-SC(DBCO-PEG-NHS) is a chemical compound that is widely used in pharmaceutical research and development. It is a derivative of polyethylene glycol (PEG) that is functionalized with two distinct chemical groups: Dibenzocyclooctyne (DBCO) and N-hydroxysuccinimide (NHS).

The DBCO group is an alkene-based cyclooctyne structure that is known for its bioorthogonal reactivity. It is widely used in click chemistry to specifically react with azide-modified biomolecules. The NHS group, on the other hand, is an amine-reactive ester that is commonly used to modify primary amines on proteins and peptides.

The unique combination of DBCO and NHS functional groups in DBCO-PEG-SC makes it a highly useful compound for pharmaceutical research and development. It can be used to modify peptides, proteins, and small molecules, enabling the development of novel drug candidates with improved therapeutic potential. Additionally, DBCO-PEG-SC has been used in drug delivery systems and in the development of imaging agents for diagnostic purposes.