DBCO-PEG-OH(DBCO-PEG-Hydroxy) consists of three main functional groups: Dibenzocyclooctyne (DBCO), polyethylene glycol (PEG), and a hydroxy group.
The DBCO functional group is commonly used in bioconjugation and labeling applications, as it can undergo a highly specific reaction with azide groups, resulting in a stable and bioorthogonal linkage. The PEG functional group is widely known for its ability to enhance solubility, reduce immunogenicity, and improve pharmacokinetics of various drugs. Lastly, the hydroxy group can participate in a range of chemical reactions, including esterification, etherification, and amidation.
The combination of these functional groups in DBCO-PEG-OH makes it a versatile compound for drug delivery and targeting applications. By conjugating drugs or targeting molecules to it, researchers can improve the efficacy, specificity, and selectivity of the drug, while reducing off-target effects and toxicity.
|AP15140||DBCO-PEG-OH, MW 2K||2000||≥95%||Pricing|