Cholesterol-PEG-Azide (Cholesterol-PEG-N3, CLS-PEG-N3) is a linear heterobifunctional PEG reagent with cholesterol on one end and N3 groups on the other, and the lipid moiety is used to encapsulate hydrophobic therapeutic agents. It can be used to prepare liposomes and other micelles as a drug delivery system to shorten the circulation time of encapsulated drugs. They can also be used in non-viral transfection reagents.
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