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HO-PEG-acid contains a carboxylic acid functional group (-COOH) at one end of a PEG chain.

Carboxylic acid functional groups are known for their ability to form ester bonds with hydroxyl groups, making HO-PEG-acid a useful tool in drug delivery systems. By covalently attaching the PEG chain to a drug molecule through an ester bond, the resulting conjugate can exhibit improved solubility, stability, and pharmacokinetic properties, leading to enhanced therapeutic efficacy and reduced side effects.

HO-PEG-acid can also be employed as a linker molecule in the synthesis of antibody-drug conjugates (ADCs). ADCs are a promising class of anticancer therapeutics that combine the specificity of monoclonal antibodies with the cytotoxicity of small molecule drugs. The carboxylic acid group of HO-PEG-acid can be used to attach the PEG chain to the antibody, while the other end can be conjugated to the cytotoxic drug molecule via a linker molecule.


Cat# Name Structure M.W. Purity Pricing
AP13488HO-PEG-acid, MW 1K1000≥95% Pricing
AP13497HO-PEG-acid, MW 2K2000≥95% Pricing
AP13512HO-PEG-acid, MW 3.5K3500≥95% Pricing
AP13526HO-PEG-acid, MW 5K5000≥95% Pricing
AP13527HO-PEG-acid, MW 10K10000≥95% Pricing

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