M-PEG-Biotin belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains a biotin functional group attached to the middle carbon atom of a PEG chain. The biotin group is known for its high affinity for avidin and streptavidin, making M-PEG-Biotin a valuable tool in the field of pharmaceutical research and development.
M-PEG-Biotin has been widely utilized in the development of novel drug delivery systems, such as targeted drug delivery and imaging agents. Its unique chemical properties allow for the conjugation of therapeutic agents, such as proteins, peptides, and antibodies, to the PEG chain via biotin-streptavidin interactions. The resulting conjugates exhibit enhanced targeting specificity, increased circulation time, and reduced non-specific binding, leading to improved therapeutic efficacy and reduced side effects.
In addition to its use in drug delivery systems, M-PEG-Biotin has also been employed in various biomedical applications, such as cell labeling and protein purification. Its high affinity for avidin and streptavidin allows for the efficient and specific immobilization of biomolecules onto surfaces or beads, facilitating their isolation and analysis.
