Biotin-PEG-OH is a polymer that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains a biotin functional group, which is a vitamin that plays an essential role in various biological processes, attached to a PEG chain. The PEG chain acts as a linker between the biotin group and other molecules.
Biotin-PEG-OH has been widely used in the development of novel drug delivery systems, diagnostics, and imaging agents. Its unique chemical properties allow for the covalent attachment of biotinylated molecules, such as proteins, peptides, and antibodies, to the PEG chain. The resulting conjugates exhibit improved stability, increased solubility, and prolonged circulation time in vivo, leading to enhanced therapeutic efficacy and reduced side effects.
In addition to its use in drug delivery systems, Biotin-PEG-OH has also been employed as a surface modifier in various biomedical applications. For example, it can be immobilized onto the surface of medical devices or implants to improve biocompatibility and reduce immune response.
