Azide-PEG-Epoxide(N3-PEG-EPO) consists of three important functional groups, namely azide, polyethylene glycol (PEG), and epoxide. Azide, a nitrogen-containing group, is widely used in chemical biology as a bio-orthogonal handle for specific labeling of biological molecules. PEG, a hydrophilic polymer, is used to improve the solubility, stability, and pharmacokinetic properties of drugs. Epoxide, a three-membered cyclic ether, is a reactive group that can undergo ring-opening reactions with various nucleophiles to form covalent bonds.
The combination of these functional groups in Azide-PEG-Epoxide makes it a useful tool for various applications in pharmaceutical research and development. For instance, the azide group can be used to selectively label proteins or peptides with fluorophores or other probes for imaging or tracking purposes. The PEG moiety can enhance the solubility of poorly soluble drugs, increase their half-life, and reduce their immunogenicity. The epoxide group, on the other hand, can be used to covalently link drugs to targeting molecules such as antibodies or peptides, leading to the development of targeted drug delivery systems.
|AP15147||N3-PEG-EPO, MW 2K||2000||≥95%||Pricing|