OPSS-PEG-SVA

OPSS-PEG-SVA is a linear bifunctional modified PEG containing an ortho-pyridyl disulfide at one end and a bifunctional polyethylene glycol with pentanoylsuccinimide at the other end. N-hydroxysuccinimide (NHS) active ester can form a physiologically stable amide bond with the amine group of lysine under mild reaction conditions. Ortho-pyridyl disulfides can selectively react with thiols or thiols to form oxidation-reduction reversible disulfide bonds.