M-PEG-Lys-NHS ester contains a lysine functional group (-NH2) attached to the middle carbon atom of a PEG chain, which is activated by an NHS ester group. The lysine group is known for its ability to react with carboxylic acids or other NHS-activated molecules, making M-PEG-Lys-NHS ester a valuable tool in the field of pharmaceutical research and development.
M-PEG-Lys-NHS ester has been extensively utilized in the development of peptide and protein conjugates. Its unique chemical properties allow for the covalent attachment of therapeutic agents, such as antibodies or enzymes, to the PEG chain via lysine residues. The resulting conjugates exhibit improved stability, increased solubility, and prolonged circulation time in vivo, leading to enhanced therapeutic efficacy and reduced immunogenicity.
In addition to its use in drug conjugation, M-PEG-Lys-NHS ester has also been employed as a surface modifier in various biomedical applications. For example, it can be immobilized onto the surface of medical devices or implants to improve biocompatibility and reduce immune response.
|AP13390||m-PEG-Lys-NHS ester, MW 20K||20000||≥95%||Pricing|
|AP13394||m-PEG-Lys-NHS ester, MW 40K||40000||≥95%||Pricing|