Lipoamide-PEG-Mal is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound consists of a PEG chain attached to a lipoamide molecule via a maleimide functional group (-Mal). The maleimide group is known for its ability to react with thiol groups present in other molecules, making Lipoamide-PEG-Mal a useful tool in the field of pharmaceutical research and development.
Lipoamide-PEG-Mal has been extensively utilized in the development of novel drug delivery systems, such as antibody-drug conjugates (ADCs). Its unique chemical properties allow for the covalent attachment of cytotoxic agents to antibodies via maleimide-thiol chemistry, resulting in ADCs with enhanced specificity and efficacy in cancer therapy. The PEG chain also provides improved solubility and reduced immunogenicity for the conjugated antibody.
Lipoamide-PEG-Mal
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP11416 | Lipoamide-PEG3-Mal | Pricing | |
| AP11417 | Lipoamide-PEG11-Mal | Pricing |
