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Propargyl-PEG-acid(Acid-PEG-Alkyne) is a chemical compound belonging to the class of polyethylene glycol (PEG) derivatives, which contains a carboxylic acid functional group (-COOH) attached to the end of a PEG chain via a propargyl linker (-C≡CH). The propargyl group is an alkyne functional group that allows for click chemistry reactions with azide-functionalized molecules.

The carboxylic acid group in Propargyl-PEG-acid offers a range of chemical reactivity, including the ability to form amide bonds with amino groups, ester bonds with hydroxyl groups, and covalent linkage to metal ions. It is also a negatively charged group at physiological pH, which can be exploited for targeted drug delivery via electrostatic interactions.

Propargyl-PEG-acid has been widely used in the development of various drug delivery systems, including polymeric micelles, liposomes, and nanoparticles. The click chemistry reaction between the propargyl group and azide-functionalized targeting ligands or drugs provides a facile method to incorporate specific functional moieties into the PEG chain, enabling the selective and efficient delivery of drugs to target sites.


Cat# Name Structure M.W. Purity Pricing
AP12267propargyl-PEG1-acid128.13≥95% Pricing
AP10290Propargyl-PEG2-acid172.18≥95% Pricing
AP10291Propargyl-PEG3-acid216.23≥95% Pricing
AP10292Propargyl-PEG4-acid260.28≥95% Pricing
AP10293Propargyl-PEG5-acid304.34≥95% Pricing
AP10294Propargyl-PEG6-acid348.39≥95% Pricing
AP12268propargyl-PEG7-acid392.45≥95% Pricing
AP12269propargyl-PEG8-acid436.5≥95% Pricing
AP12270propargyl-PEG10-acid524.6≥95% Pricing
AP10295Propargyl-PEG13-acid656.74≥95% Pricing
AP12271propargyl-PEG14-acid700.82≥95% Pricing
AP10296Propargyl-PEG25-acid1185.34≥95% Pricing

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