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Ms-PEG-t-butyl ester(Mesyl-PEG-t-butyl ester) is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains a mesylate functional group (-SO2CH3) attached to the end of a PEG chain, and a t-butyl ester group (-COOC(CH3)3) attached to the other end. The mesylate group is known for its ability to undergo substitution reactions, while the t-butyl ester group provides protection for the PEG chain.

Mesyl-PEG-t-butyl ester has been widely used in pharmaceutical research and development as a building block for the synthesis of PEGylated drugs and drug delivery systems. Its unique chemical properties allow for the site-specific conjugation of therapeutic agents to the PEG chain, leading to improved drug solubility, stability, and pharmacokinetics.

In addition, mesyl-PEG-t-butyl ester has been utilized in the development of prodrugs, which are biologically inactive compounds that can be converted into active drugs in vivo. The t-butyl ester group acts as a protective group that can be selectively removed in the presence of specific enzymes, releasing the active drug and providing targeted therapeutic effects.

Ms-PEG-t-butyl ester

Cat# Name Structure M.W. Purity Pricing
AP11911Ms-PEG2-t-butyl ester312.38≥95% Pricing
AP11912Ms-PEG4-t-butyl ester400.48≥95% Pricing
AP11913Ms-PEG8-t-butyl ester576.7≥95% Pricing
AP11914Ms-PEG10-t-butyl ester664.8≥95% Pricing
AP11915Ms-PEG13-t butyl ester752.91≥95% Pricing

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