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Mono-sulfone acid is a chemical compound that belongs to the class of sulfonic acids. It contains a sulfone functional group (-SO2-) and a carboxylic acid group (-COOH) attached to a carbon atom.

Mono-sulfone acid has been extensively utilized in the development of drugs targeting various diseases, including cancer, inflammation, and viral infections. Its sulfone group allows for the formation of covalent bonds with biomolecules, such as proteins and nucleic acids, leading to enhanced potency and selectivity. In addition, the carboxylic acid group can be used to modify the physicochemical properties of the compound, such as solubility and lipophilicity, to improve its pharmacokinetics and pharmacodynamics.

Mono-sulfone acid has been utilized in the design and synthesis of prodrugs, which are inactive compounds that are converted into active drugs upon metabolism. The sulfone and carboxylic acid groups of Mono-sulfone acid can be used to attach pro-moieties that are cleaved by enzymes in the body, releasing the active drug. This approach can improve the selectivity and reduce the toxicity of drugs.

Mono-sulfone Acid

Cat# Name Structure M.W. Purity Pricing
AP12679Mono-sulfone Acid332.37≥95% Pricing

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