Mal-PEG-amine

Maleimide-PEG-Amine is a versatile chemical reagent with two key functional groups: a maleimide group (-Mal) and an amine group (-NH₂), located at opposite ends of a polyethylene glycol (PEG) chain. This unique structure makes it highly useful in drug delivery and bioconjugation.

Key Features:

• Maleimide Group: Specifically reacts with thiol groups (-SH) to form stable thioether bonds. This property is essential for linking with thiol-containing molecules, such as proteins and peptides.
• Amine Group: Allows further chemical modifications through amide bond formation, adding flexibility for additional conjugation or labeling.

Applications:

1. Drug Delivery Systems:
   • Therapeutic Conjugates: Facilitates the attachment of therapeutic agents to the PEG chain, enhancing stability, solubility, and circulation time. This leads to more effective treatments with fewer side effects.
2. Crosslinking Reagent:
   • Biomolecule Crosslinking: Ideal for creating stable conjugates of proteins, nucleic acids, and other biomolecules, useful in diagnostic assays and therapeutic applications.

Maleimide-PEG-Amine is a valuable tool in pharmaceutical research and biomedicine, offering improved stability and functionality for various applications.

ity to form stable, functional conjugates with improved properties.