Maleimide-PEG-Amine is a versatile chemical reagent with two key functional groups: a maleimide group (-Mal) and an amine group (-NH₂), located at opposite ends of a polyethylene glycol (PEG) chain. This unique structure makes it highly useful in drug delivery and bioconjugation.
Key Features:
- Maleimide Group: Specifically reacts with thiol groups (-SH) to form stable thioether bonds. This property is essential for linking with thiol-containing molecules, such as proteins and peptides.
- Amine Group: Allows further chemical modifications through amide bond formation, adding flexibility for additional conjugation or labeling.
Applications:
- Drug Delivery Systems:
- Therapeutic Conjugates: Facilitates the attachment of therapeutic agents to the PEG chain, enhancing stability, solubility, and circulation time. This leads to more effective treatments with fewer side effects.
- Crosslinking Reagent:
- Biomolecule Crosslinking: Ideal for creating stable conjugates of proteins, nucleic acids, and other biomolecules, useful in diagnostic assays and therapeutic applications.
Maleimide-PEG-Amine is a valuable tool in pharmaceutical research and biomedicine, offering improved stability and functionality for various applications.
ity to form stable, functional conjugates with improved properties.
Mal-PEG-amine
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP11472 | Mal-PEG2-amine TFA salt | Pricing | |
| AP10050 | Mal-PEG3-amine | Pricing | |
| AP13269 | Mal-PEG4-amine TFA salt | Pricing |
