HyNic-PEG-Azide is a molecule that belongs to the family of clickable PEGylation reagents. It is a bifunctional compound containing both a hydrazinonicotinamide (HyNic) group and an azide group. The HyNic group enables the attachment of the molecule to a wide range of biomolecules, while the azide group allows for the conjugation of the modified biomolecule to other molecules using click chemistry. The use of HyNic-PEG-Azide in pharmaceutical research and development is highly advantageous as it allows for the targeted delivery of drugs to specific cells or tissues, increasing the efficacy and minimizing unwanted side effects. Additionally, it can be used for the preparation of diagnostic imaging agents, such as PET tracers, for non-invasive imaging of disease states.