Folate-PEG-NHS ester(Folic Acid-PEG-NHS ester) is a compound that is widely used in drug research and development. It belongs to the class of functional groups known as esters, which are formed by the reaction of an alcohol with a carboxylic acid. Folate-PEG-NHS ester is a modified form of the B vitamin folate, which is essential for the synthesis of DNA and other important cellular processes.
In drug research and development, folate-PEG-NHS ester is used as a targeting agent for delivering drugs to cancer cells that overexpress folate receptors. This targeting approach is called folate receptor-mediated targeting, and it has shown great promise in improving the efficacy and specificity of anticancer drugs.
Folate-PEG-NHS ester is also used as a linker molecule for conjugating drugs to other targeting agents, such as antibodies or peptides. This approach can enhance the selectivity and binding affinity of drugs to their intended targets, while minimizing off-target effects and toxicity.
Folate-PEG-NHS ester
Cat# | Name | Structure | Pricing |
---|---|---|---|
AP10011 | Folate PEG3 NHS ester | Pricing | |
AP15300 | Folate PEG10 NHS ester | Pricing |