Folate-PEG-Hydrazide is a compound for targeted drug delivery and bioconjugation. It features folic acid for cancer cell targeting, a PEG spacer for stability, and a hydrazide group for binding to carbonyl-containing molecules.
Folate-PEG-hydrazide
| Cat# | Name | Structure | Pricing |
|---|---|---|---|
| AP12977 | Folate-PEG1-hydrazide | Pricing | |
| AP12978 | Folate-PEG2-hydrazide | Pricing |
Folate-PEG-Hydrazide (Folic Acid-PEG-Hydrazide)
Folate-PEG-Hydrazide is a compound designed for targeted drug delivery and bioconjugation. It combines folic acid for cancer cell targeting, a PEG spacer for better solubility and stability, and a hydrazide group for efficient binding to carbonyl-containing molecules.
Key Features:
- Folic Acid:
- Targets folate receptors, often found on cancer cells.
- Enables precise delivery of drugs or imaging agents.
- PEG Spacer:
- Improves solubility and biocompatibility.
- Reduces steric hindrance for more effective conjugation.
- Hydrazide Group:
- Binds to aldehydes and ketones, forming stable hydrazone bonds.
- Makes it easy to attach drugs, proteins, or other biomolecules.
Applications:
- Targeted Drug Delivery:
- Sends therapeutic agents directly to cancer cells.
- Increases treatment precision while reducing side effects.
- Bioconjugation:
- Links to aldehyde- or ketone-containing molecules for advanced therapies.
- Develops drug conjugates and imaging agents.
- Diagnostics:
- Creates tools for accurate tumor detection and monitoring.
Benefits:
- Better Targeting:
- Delivers drugs or agents directly to cancer cells via folate receptors.
- Improved Stability:
- PEG spacer increases solubility and biocompatibility.
- Versatile Use:
- Hydrazide group allows for easy attachment to a range of molecules.
Folate-PEG-Hydrazide is a powerful tool for targeted therapies and diagnostics. It ensures precise delivery, stability, and flexibility, making it ideal for advanced biomedical applications.