Trifluoroethyl-PEG-Aminooxy is a type of polyethylene glycol (PEG) derivative that contains a trifluoroethyl group and an aminooxy functional group. The trifluoroethyl group is a nonpolar, fluorinated hydrocarbon chain that can increase the lipophilicity of molecules, making them more soluble in organic solvents and enhancing their bioavailability. The aminooxy group is a reactive functional group that can form stable oxime linkages with carbonyl groups, allowing for conjugation with various molecules. Trifluoroethyl-PEG-Aminooxy has been extensively used in pharmaceutical research and development as a versatile linker for drug delivery systems and as a tool for site-specific conjugation of bioactive molecules. Its unique properties make it a promising candidate for the development of new drug candidates with improved pharmacokinetics and therapeutic efficacy.