VdU (5-Vinyl-2′-deoxyuridine) CAS:55520-67-7 is a synthetic analog of thymidine that is cell permeable and incorporates into replicating DNA via a copper-free olefin-tetrazine reaction (also known as an inverse electron demand Diels-Alder junction or IEDDA) to introduce biotin or fluorescent dye groups, the resulting vinyl-functionalized DNA can be detected and used for subsequent DNA purification or cell imaging tasks. Can be used as a replacement for BrdU (5-Bromo-2′-deoxyuridine) or copper catalysts requiring 5-EdU (5-Ethynyl-2′-deoxyuridine) Measure de novo DNA synthesis during the S phase of the cell cycle.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
