SPDP-PEG9-Acid
SPDP-PEG9-acid is a specialized molecule used in research and drug development. It combines an SPDP group, which attaches to thiols (-SH), with a PEG chain of 9 units that ends with a carboxylic acid group. This design makes it useful for connecting different molecules in experiments.
Main Features
- SPDP Group
- Binds to thiol groups to form a breakable bond.
- Allows controlled release under certain conditions.
- Carboxylic Acid Group
- Connects to molecules with amines (-NH₂) to form a stable link.
- PEG Spacer (9 Units)
- Increases solubility in water.
- Adds flexibility to reduce crowding between attached molecules.
SPDP-PEG9-acid Uses
- Building PROTACs
- Used as a bridge in PROTACs, which are tools for targeting and breaking down unwanted proteins in cells.
- Attaching Molecules
- Helps link proteins, peptides, or other molecules to surfaces or carriers, which can be used in medical and research applications.
Chemical Information
- Formula: C₂₉H₅₀N₂O₁₂S₂
- Molecular Weight: 682.84 g/mol
- Purity: Usually 95% or higher
- Solubility: Mixes easily in water and some solvents.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
