PC DBCO-NHS Ester (CAS: 2055025-02-8)
Overview: PC DBCO-NHS Ester is a specialized reagent featuring an NHS carbonate group and a DBCO group. It includes a photocleavable nitrobenzyloxyl spacer that can be efficiently cleaved under UV light to release conjugated molecules.
Key Features:
- NHS Carbonate Group: Reacts with amine-containing biomolecules for effective conjugation.
- DBCO Group: Facilitates fast and efficient copper-free click chemistry reactions with azide-bearing biomolecules, ensuring high yield and specificity.
- Photocleavable Spacer: The nitrobenzyloxyl group allows for controlled cleavage under UV light, enabling the release of conjugated molecules as needed.
Applications:
- Bioconjugation: Ideal for linking biomolecules with high precision and efficiency.
- Controlled Release: Utilize the photocleavable spacer for applications requiring the release of conjugated molecules upon UV exposure.
Benefits:
- Efficient Reactions: The DBCO group ensures high-yield, copper-free click chemistry with azide-tagged targets.
- Versatile Use: Suitable for a variety of bioconjugation and controlled release applications.
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