Mal-PEG-HZ (Mal-PEG-Hydrazide), MW 1K is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This compound contains both a maleimide functional group (-CONHCH=CHC(=O)-) and a hydrazide functional group (-CONHNH2) attached to the PEG chain. The maleimide group is known for its ability to react with sulfhydryl groups (-SH) of cysteine residues in proteins or peptides, while the hydrazide group can react with aldehydes or ketones, making Maleimide-PEG-Hydrazide a versatile tool in the field of pharmaceutical research and development.
Maleimide-PEG-Hydrazide has been extensively utilized in the development of site-specific protein conjugation and modification strategies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
