GGFG-amino-CH2O-acetyl Exetecan CAS:1599440-12-6 (Exatecan-2-(aminomethoxy)acetamide-Gly-Phe-Gly-Gly) is a hexacyclic chemical compound analogous to camptothecin, featuring a terminal four-amino-acid group. This versatile compound is designed for use as a payload in antibody-drug conjugate (ADC) research. As an inhibitor of DNA topoisomerase I, Exatecan mesylate plays a critical role in DNA replication, transcription, and recombination processes.
Introduction to the application:
In pharmaceutical research and development, GGFG-amino-CH2O-acetyl Exetecan serves as an innovative payload for targeted ADCs. Its unique amino acid linker is cleavable, making it a valuable tool for drug delivery. Exatecan mesylate’s ability to inhibit DNA topoisomerase I contributes to its effectiveness against various cancer types. Available as a reagent grade compound for research purposes, GGFG-amino-CH2O-acetyl Exetecan is driving the development of more effective and safer cancer therapeutics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
