Biotin-PEG4-amido-methyltetrazine is a cutting-edge, bifunctional small molecule that combines biotin, a vital coenzyme for numerous enzymes, with a polyethylene glycol (PEG) linker and a methyltetrazine moiety. The PEG4 linker imparts solubility and flexibility, while the methyltetrazine group enables rapid bioorthogonal reactions, collectively enhancing the molecule’s stability, bioavailability, and target specificity in pharmaceutical applications.
In pharmaceutical research and development, Biotin-PEG4-amido-methyltetrazine is a versatile tool for bioconjugation, facilitating targeted drug delivery and real-time imaging. Its ability to undergo rapid, selective reactions with trans-cyclooctene (TCO)-labeled biomolecules promotes site-specific conjugation, enabling researchers to develop targeted therapies, diagnostics, and theranostics with high precision, minimal toxicity, and improved pharmacokinetics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
