3-(3-Methyl-3H-diazirin-3-yl)propanoic acid

3-(3-Methyl-3H-diazirin-3-yl)propanoic acid CAS:25055-86-1 is a chemical compound that is commonly used in biochemical research as a photo-crosslinking agent. It belongs to the class of diazirine-containing compounds, which can be activated by UV light to form highly reactive carbene intermediates. These carbene intermediates can covalently modify or crosslink biomolecules in close proximity, allowing for the study of protein-protein interactions, protein-ligand binding, and other biological processes.

3-(3-Methyl-3H-diazirin-3-yl)propanoic acid is a small molecule that is easy to incorporate into peptides, proteins, or other biomolecules. It is commonly used in chemical biology and drug discovery to identify the protein targets of small molecule compounds, to study protein-protein interactions, and to map the binding sites of ligands on proteins. The reactive carbene intermediate generated by 3-(3-Methyl-3H-diazirin-3-yl)propanoic acid can covalently modify amino acid residues in proteins, including lysine, arginine, and histidine, which can be identified and analyzed by various biochemical methods.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.