2-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]ethan-1-amine CAS:1450752-97-2 is a small molecule with a unique functional group, a diazirine ring. Diazirines are photo-reactive groups that can be activated with UV light, making them useful in a variety of applications. In pharmaceutical research and development, diazirine-containing molecules like 2-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]ethan-1-amine are often used to study protein-protein interactions and protein-ligand interactions. By attaching a diazirine group to a drug candidate or a protein of interest, researchers can use UV light to “crosslink” the molecule with its binding partners, allowing them to identify and study the interacting proteins. Diazirine-containing molecules have also been used in drug discovery to identify new targets and to study drug metabolism and pharmacokinetics.
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