5′-O-(4,4-Dimethoxytrityl)-2′-OMe Inosine-3′-CED Phosphoramidite (CAS 128219-85-2) is a 2′-O-methyl inosine phosphoramidite used in RNA oligonucleotide synthesis. The 2′-O-methyl modification increases the stability of RNA sequences and improves their resistance to enzymatic degradation. The dimethoxytrityl (DMT) group protects the 5′ hydroxyl group, allowing for precise incorporation of inosine into RNA strands during solid-phase synthesis.
Key Features:
- CAS Number: 128219-85-2
- Chemical Structure: 2′-O-methyl inosine with a 5′-O-dimethoxytrityl (DMT) group
- Function: Building block for RNA oligonucleotide synthesis
- Protection Groups: DMT protection on the 5′ hydroxyl group
- Applications:
- RNA oligonucleotide synthesis
- Enhances RNA stability for research, diagnostics, and therapeutic development
5′-O-(4,4-Dimethoxytrityl)-2′-OMe Inosine-3′-CED Phosphoramidite provides increased stability and precision in RNA synthesis, making it valuable for advanced genetic research and therapeutic applications.
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