Azido-PEG2-t-butyl ester
This product is a high-purity PEG linker with an azide specifically for click chemistry and a t-butyl ester as an acid-labile carboxyl protecting group. Its PEG2 spacer boosts solubility, reduces steric hindrance, and enables efficient conjugation for bioorthogonal labeling, drug delivery, and bioconjugation.
Key Features and Benefits:
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Dual Functional Groups: Azide for click chemistry and t-butyl ester for protected carboxylic acid.
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PEG2 Spacer: Enhances hydrophilicity and reduces steric interference.
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Orthogonal Reactivity: Allows stepwise functionalization and selective deprotection.
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High Purity: Ensures consistent, reproducible results in sensitive workflows.
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Versatile: Suitable for use in both aqueous and organic reaction conditions.
Applications:
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Bioorthogonal Conjugation: Click chemistry with alkynes for probe or drug attachment.
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Drug Delivery: Enable linker design for controlled payload release.
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Bioconjugation: Functionalize peptides, antibodies, and other biomolecules.
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Polymer and Surface Modification: Introduce reactive groups for downstream conjugation.
Storage and Handling:
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Storage: Store at –20 °C, away from light and moisture.
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Handling: Use anhydrous solvents (e.g., DMSO, DMF) and avoid moisture to preserve reactivity.
Azido-PEG2-t-butyl ester provides a reliable, orthogonally protected PEG linker for constructing multifunctional molecules in chemical biology, medicinal chemistry, and advanced materials science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
