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CAS:231278-20-9
N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine $110.00 – $350.00
XMD 8-92

Catalog #: AP14269
Name: XMD 8-92
Chemical Formula: C26H30N6O3
Molecular Weight: 474.60
CAS: 1234480-50-2
Purity: ≥95%
Availability: In Stock

XMD 8-92

$120.00 – $450.00

UnitPriceQuantity
10 mg$120
25 mg$260
50 mg$450

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SKU: AP14269 Category:
Description

XMD 8-92 is an ERK5 (BMK1) and BRD4 inhibitor (K d of 80 and 190 nM, respectively). Selective for 402 different kinases, also inhibits DCAMKL2, PLK4 and TNK1 (Kd values of 190, 600 and 890 nM). XMD 8-92 has been shown to block growth factor-induced cellular BMK1 activation and reduce BMK1 activity in in vitro kinase assays. XMD 8-92 reduces the BMK1-dependent transactivation activity of MEF2C. Blocks tumor cell proliferation and tumor-associated angiogenesis.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.

Synonyms
  • XMD8-92
  • 1234480-50-2
  • XMD 8-92
  • 2-[[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-B][1,4]benzodiazepin-6-one
  • 2-[2-ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one
  • 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
  • 2-((2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
  • J-004942 Q27089252 2-((2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one 2-(2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one 2-[2-Ethoxy-4-(4-hydroxypiperidin-1-yl)anilino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one 5-{[2-ETHOXY-4-(4-HYDROXYPIPERIDIN-1-YL)PHENYL]AMINO}-2,9-DIMETHYL-2,4,6,9-TETRAAZATRICYCLO[9.4.0.0(3),?]PENTADECA-1(15),3,5,7,11,13-HEXAEN-10-ONE
Shipping & Delivery
Ships within: 24 hours
Storage condition: -20 ° C
Shipping: Ambient Temperature

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