t-Boc-N-Amido-PEG9-propargyl contains a propargyl group and a Boc protected amine group. The propargyl group can be reacted with azide-bearing compounds through copper catalyzed Click Chemistry to yield a stable triazole linkage. The t-Boc protected amine can be deprotected under mild acidic conditions to afford a free amine. The PEG spacer increases the aqueous solubility of the resulting compound.
T–Boc–N–Amido–PEG9–propargyl (also known as BAP) is a type of chemical compound used in bioconjugation, a process used to link two molecules together. It is a polyethylene glycol (PEG) derivative containing a propargyl group and an amine–reactive Boc–protected amide group. The propargyl group can be used to attach the molecule to a variety of other molecules, while the Boc–protected amide group enables the molecule to react with other molecules containing amine groups.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
