SPDP-Gly-Pro-acid TEA salt is a versatile reagent featuring a pyridyldithiol (SPDP) group, a glycine-proline dipeptide, and a carboxylic acid with a tetraethylammonium counterion. The SPDP group facilitates disulfide bond formation, while the Gly-Pro dipeptide imparts stability and the carboxylic acid offers conjugation possibilities.
In pharmaceutical R&D, SPDP-Gly-Pro-acid TEA salt serves as a potent crosslinking agent, enabling the conjugation of bioactive molecules to carriers or targeting moieties. Its unique combination of functional groups allows for site-specific and controlled conjugation, enhancing the efficacy, selectivity, and pharmacokinetics of drug delivery systems. Additionally, it is employed in the development of antibody-drug conjugates, protein therapeutics, and targeted drug delivery platforms.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
