Propargyl-PEG3-CH2CO2H(Propargyl-PEG3-Carboxylic Acid) CAS:944561-46-0, is a high-purity, water-soluble, and biocompatible polyethylene glycol (PEG) derivative. It features a propargyl group at one end and a carboxylic acid moiety at the other, providing excellent versatility in bioconjugation and click chemistry applications. Its unique PEG3 linker imparts increased solubility and reduced immunogenicity, making it a valuable tool in pharmaceutical research and development.
In drug development, Propargyl-PEG3-CH2CO2H has been utilized for the site-specific conjugation of therapeutic agents, including small molecules, peptides, and proteins, to improve their pharmacokinetic and pharmacodynamic properties. It has also been employed in the development of targeted drug delivery systems and antibody-drug conjugates, enhancing drug specificity and reducing off-target effects. Additionally, its click chemistry compatibility facilitates the synthesis of complex bioactive molecules and the construction of multifunctional nanomaterials for theranostic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
