Norbornene-PEG6 Pyrene

Norbornene-PEG6-Pyrene

This product is a multifunctional PEG linker containing a norbornene group, a PEG6 spacer, and a pyrene moiety. It enables bioorthogonal click chemistry with tetrazines and fluorescence-based applications, specifically combining reactivity with photophysical properties.

Key Features and Benefits

• Norbornene Group: Reacts rapidly with tetrazines via IEDDA click chemistry.

• Pyrene Moiety: Provides strong fluorescence for detection and imaging.

• PEG6 Spacer: Improves solubility and reduces steric hindrance.

• Dual Functionality: Combines click reactivity with fluorescent tagging.

• High Purity: Ensures reproducible performance in sensitive workflows.

Applications

• Bioconjugation: Links tetrazine-modified biomolecules with fluorescent labeling.

• Probe Development: Builds multifunctional probes for imaging and diagnostics.

• Drug Delivery: Serves as a scaffold with orthogonal and fluorescent handles.

• Material Science: Functionalizes polymers and nanostructures with click and fluorescent properties.

Storage and Handling

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to light.

This product integrates norbornene click reactivity with pyrene fluorescence in a PEG6 scaffold, specifically providing a versatile tool for conjugation and probe design.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.