MMAF (Monomethyl Auristatin F) CAS:745017-94-1 is a potent cytotoxic microtubule inhibitor and a crucial functional group in antibody-drug conjugates (ADCs). As a synthetic analog of dolastatin 10, It exhibits impressive antitumor activity by disrupting microtubule dynamics, leading to cell cycle arrest and subsequent apoptosis in targeted cancer cells.
MMAF plays an indispensable role in the creation of effective ADCs for targeted cancer therapy. By linking it to a specific monoclonal antibody, researchers can harness its cytotoxic potential to selectively eliminate cancer cells while sparing healthy tissues.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.