Methyltetrazine-PEG8-amine HCl salt is a versatile, water-soluble, and biocompatible linker molecule composed of a methyltetrazine moiety, an 8-unit polyethylene glycol (PEG) spacer, and an amine functional group. The tetrazine moiety exhibits rapid bioorthogonal reactivity, enabling efficient conjugation with strained alkene or alkyne partners in click chemistry reactions, while the PEG spacer imparts hydrophilicity and flexibility.
In pharmaceutical research and development, Methyltetrazine-PEG8-amine HCl salt serves as an effective bioconjugation agent for drug delivery systems, targeted therapeutics, and imaging probes. Its unique characteristics facilitate selective conjugation of biomolecules, enhancing pharmacokinetics, biostability, and bioavailability. Utilized in antibody-drug conjugates, small molecule therapeutics, and nucleic acid delivery, this linker has revolutionized targeted drug development, advancing precision medicine and expanding the boundaries of molecular diagnostics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
