Maleimido-mono-amide-NOTA (CAS: 1295584-83-6) is a bifunctional chelator featuring a maleimide group for thiol-specific conjugation and a NOTA (1,4,7-triazacyclononane-N,N’,N”-triacetic acid) backbone for stable metal ion binding. It is widely used in radiolabeling applications, allowing for targeted conjugation to biomolecules containing thiol groups, such as cysteine residues. This makes it ideal for PET and SPECT imaging, as well as other diagnostic and therapeutic applications.
Key Features:
- Type: Bifunctional chelator
- Function: Thiol-specific conjugation; strong metal ion chelation
- Applications:
- Radiolabeling for PET and SPECT imaging
- Targeted diagnostics
- Conjugation to thiol-containing biomolecules
- Biomedical imaging
- Advantages: Specific thiol conjugation, strong metal binding, versatile imaging use
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