Mal-PEG3-CH2 NHS ester (CAS: 2230016-26-7)
Description:
Mal-PEG3-CH₂ NHS Ester is a versatile PEG-based linker with a maleimide group for thiol binding and an NHS ester for amine conjugation. The PEG3-CH₂ spacer improves solubility and flexibility, making it ideal for targeted drug delivery, protein labeling, and diagnostic applications.
Key Features:
- Maleimide Group: Binds specifically to thiol groups on proteins and peptides.
- NHS Ester: Reacts with primary amines for stable conjugation.
- PEG3-CH₂ Spacer: Enhances solubility and reduces steric hindrance.
Applications:
- Antibody-Drug Conjugates (ADCs): Links antibodies to drugs for targeted therapies.
- Protein and Peptide Labeling: Enables specific and stable labeling in research.
- Diagnostics: Attaches biomolecules in assays and biosensors.
- Nanoparticle Functionalization: Binds functional molecules to nanoparticles for delivery and imaging.
Storage:
Store in a cool, dry, dark place to maintain stability.
Mal-PEG3-CH₂ NHS Ester is widely used in bioconjugation for its reliable binding and enhanced solubility, ideal for drug delivery, diagnostics, and protein labeling.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.