Mal-PEG2-Val-Cit-PAB-PNP CAS:1345681-52-8 is a type of small molecule drug that is composed of several functional groups. The Mal (maleimide) group is a functional group that can react specifically with thiol groups on proteins, allowing the drug to be targeted to specific proteins in the body. The PEG2 group is a polyethylene glycol spacer that can help to improve the solubility and stability of the drug in solution. The Val (valine) and Cit (citrulline) groups are amino acids that are used to create a peptide bond, which is an important structural component of the drug. The PAB (p-aminobenzoic acid) group is a functional group that can be used to link the drug to other molecules, while the PNP (4-nitrophenyl) group is used as a leaving group in chemical reactions.
The combination of these functional groups in Mal-PEG2-Val-Cit-PAB-PNP is designed to create a drug that can be used to target specific proteins or biological processes in the body. The Mal group, for example, can be used to target the drug to proteins that are overexpressed in certain types of cancer cells, allowing for more targeted and effective treatment. The PEG2 spacer can help to improve the pharmacokinetic properties of the drug, while the amino acid groups are used to create a peptide bond that can increase the stability of the drug in the body. The PAB group can be used to link the drug to other molecules, such as antibodies, to create a more targeted therapy.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.