Mal-PEG1-acid
This product is a heterobifunctional PEG linker containing a maleimide group, a PEG1 spacer, and a terminal carboxylic acid. It specifically enables thiol conjugation and amide coupling, offering compact length, solubility, and dual reactivity.
Key Features and Benefits
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Maleimide Group: Reacts efficiently with thiols to form stable thioether bonds.
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Carboxylic Acid: Couples with amines to form stable amide linkages.
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PEG1 Spacer: Provides compact spacing and enhances solubility.
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Dual Reactivity: Combines thiol-specific conjugation with carboxyl coupling.
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High Purity: Ensures reproducibility in bioconjugation and synthesis workflows.
Applications
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Bioconjugation: Links thiol-containing and amine-containing biomolecules.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides PEG scaffolds with orthogonal reactive handles.
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Organic Synthesis: Serves as an intermediate for modular linker design.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates maleimide thiol reactivity with carboxyl chemistry in a PEG1 scaffold, specifically offering compact and versatile conjugation capacity.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
