Mal-PEG-NHS(Mal-PEG-SC), MW 1K consists of a polyethylene glycol (PEG) backbone that has been modified with two important functional groups, maleimide and N-hydroxysuccinimide (NHS). The maleimide group can covalently bind to thiol groups in proteins or peptides, while the NHS group reacts with amino groups to form stable amide bonds. These functional groups make MAL-PEG-NHS an ideal tool for targeted drug delivery, protein conjugation, and surface modification of medical devices.
In pharmaceutical research and development, Mal-PEG-NHS, MW 1K has been used to improve the pharmacokinetic and pharmacodynamic properties of drugs. It has been shown to increase the half-life of proteins and peptides in the bloodstream, reduce immunogenicity, and enhance the selectivity and efficacy of drug delivery. Additionally, It is useful in the production of diagnostic agents and in the development of imaging techniques for disease detection and treatment.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.