m-PEG16-acid is a high-purity, water-soluble reagent widely utilized in pharmaceutical research and development. This innovative compound features a methoxy group (OCH3) at one end and a carboxylic acid (COOH) functional group at the other, separated by a hydrophilic 16-unit polyethylene glycol (PEG) chain.
The carboxylic acid end of m-PEG16-acid enables facile conjugation to primary amine-containing biomolecules, such as peptides, proteins, and antibodies, using standard coupling techniques. Upon activation with carbodiimide reagents like EDC or DCC, the acid group forms a stable amide bond with target biomolecules.
The presence of the PEG chain improves the physicochemical properties of bioconjugates, imparting enhanced solubility, stability, and biocompatibility. Consequently, m-PEG16-acid has found extensive application in drug delivery systems, PEGylation of therapeutic proteins, and the development of antibody-drug conjugates.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
