Gimatecan CAS:292618-32-7, a potent lipophilic camptothecin analogue, is characterized by its unique indenoisoquinoline structural motif. This distinctive functional group enables the molecule to efficiently intercalate into DNA and selectively target topoisomerase I, an enzyme crucial for DNA replication and transcription processes.
Introduction to the Application:
In pharmaceutical research and development, Gimatecan has demonstrated exceptional promise as an antitumor agent. With its specific mode of action against topoisomerase I, Gimatecan has been effectively utilized in preclinical and clinical trials for the treatment of various cancers, including ovarian, gastric, and non-small cell lung cancer. Its efficacy and safety profile support its potential role as a vital therapeutic option in the fight against cancer.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
