FmocNH-PEG4-amine (CAS: 2709328-44-7)
FmocNH-PEG4-amine is a PEG derivative with an Fmoc-protected amine group and a free amine group. The Fmoc group protects the amine during peptide synthesis, while the free amine allows for further conjugation with other molecules, making it useful for creating antibody-drug conjugates (ADCs) and other bioconjugates.
Key Features:
- Fmoc Protection: Protects the amine group during peptide synthesis.
- PEG Spacer: The four-unit PEG chain enhances solubility and flexibility, reducing steric hindrance.
- Free Amine Group: Enables conjugation with other molecules for further bioconjugation applications.
Applications:
- Peptide Synthesis: Protects amine groups during peptide assembly.
- Antibody-Drug Conjugates (ADCs): Links cytotoxic drugs to antibodies for targeted delivery.
- Biomolecule Conjugation: Attaches molecules to biomolecules for research and therapeutic uses.
Handling and Storage:
- Storage: Store at -20°C, protected from light and moisture.
- Handling: Follow standard laboratory precautions when using this reagent.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
