Fmoc-Val-Ala-PAB-PFP CAS:2348406-01-7 is a type of small molecule linker that is often used in the field of bioconjugation and drug delivery. It contains several functional groups, including an Fmoc group, a valine-alanine dipeptide, a p-aminobenzyloxycarbonyl (PAB) protecting group, and a pentafluorophenyl (PFP) ester group.
The Fmoc group is used as a temporary protecting group for the amine group in the linker, which can be removed later to allow for conjugation with other molecules. The valine-alanine dipeptide is often used to improve the solubility and stability of the linker, while the PAB group can be used to target specific cells or tissues.
The PFP ester group is particularly useful, as it can react with primary amines to form stable amide bonds, which can be used to attach the linker to other molecules, such as drugs or nanoparticles. The PFP ester group is also photolabile, meaning that it can be cleaved by exposure to light, allowing for controlled release of the attached molecule.
Fmoc-Val-Ala-PAB-PFP is a valuable tool for bioconjugation and drug delivery applications, as it can improve the pharmacokinetics and efficacy of drugs, as well as reduce their toxicity and immunogenicity. Its unique combination of functional groups make it an essential component of modern pharmaceutical research, and a promising candidate for the development of targeted therapeutics in various diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
