Diazo Biotin-PEG3-azide is biotinylation reagent containing an extended PEG spacer and a terminal primary amine group. The azide group can conjugate with alkyne such as propargyl, DBCO and BCN tagged biomolecules through click chemistry to form a stable triazole linkage. The extended PEG spacer increases the aqueous solubility of the biotinylated conjugates and helps minimize steric hindrance derived from binding to strepavidin, avidin and other proteins.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.